Biological Evaluation of Double Point Modified Analogues of 1,25-Dihydroxyvitamin D(2) as Potential Anti-Leukemic Agents

Structurally similar double-point modified analogues of 1,25-dihydroxyvitamin D(2) (1,25D(2)) were screened in vitro for their pro-differentiating activity against the promyeloid cell line HL60. Their affinities towards human full length vitamin D receptor (VDR) and metabolic stability against human...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Corcoran, Aoife, Nadkarni, Sharmin, Yasuda, Kaori, Sakaki, Toshiyuki, Brown, Geoffrey, Kutner, Andrzej, Marcinkowska, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783874/
https://ncbi.nlm.nih.gov/pubmed/26840307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17020091
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