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AKT expression is associated with degree of pathologic response in adenocarcinoma of the esophagus treated with neoadjuvant therapy

BACKGROUND: Neoadjuvant chemoradiation (NCRT) has become standard in the treatment of locally advanced esophageal adenocarcinoma (EAC) with survival correlated to degree of pathologic response. The phosphatidyl inositol 3 kinase (PI3K)/protein kinase B (AKT)/mTOR pathway plays an important role in t...

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Detalhes bibliográficos
Publicado no:J Gastrointest Oncol
Main Authors: Saeed, Nadia, Shridhar, Ravi, Hoffe, Sarah, Almhanna, Khaldoun, Meredith, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783740/
https://ncbi.nlm.nih.gov/pubmed/27034781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.067
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