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Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability
Hyperpermeability of the endothelial barrier and resulting microvascular leakage are a hallmark of sepsis. Our studies describe the mechanism by which serotonin (5-HT) regulates the microvascular permeability during sepsis. The plasma 5-HT levels are significantly elevated in mice made septic by cec...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783700/ https://ncbi.nlm.nih.gov/pubmed/26956613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22747 |
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