Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups

Folate receptor α (FRα) autoantibodies (FRAAs) are prevalent in autism spectrum disorder (ASD). They disrupt the transportation of folate across the blood-brain barrier by binding to the FRα. Children with ASD and FRAAs have been reported to respond well to treatment with a form of folate known as f...

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Veröffentlicht in:Front Neurosci
Hauptverfasser: Frye, Richard E., Delhey, Leanna, Slattery, John, Tippett, Marie, Wynne, Rebecca, Rose, Shannon, Kahler, Stephen G., Bennuri, Sirish C., Melnyk, Stepan, Sequeira, Jeffrey M., Quadros, Edward
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Psychiatry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783401/
https://ncbi.nlm.nih.gov/pubmed/27013943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00080
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