Absence of Tau triggers age‐dependent sciatic nerve morphofunctional deficits and motor impairment

Dementia is the cardinal feature of Alzheimer's disease (AD), yet the clinical symptoms of this disorder also include a marked loss of motor function. Tau abnormal hyperphosphorylation and malfunction are well‐established key events in AD neuropathology but the impact of the loss of normal Tau...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Lopes, Sofia, Lopes, André, Pinto, Vítor, Guimarães, Marco R., Sardinha, Vanessa Morais, Duarte‐Silva, Sara, Pinheiro, Sara, Pizarro, João, Oliveira, João Filipe, Sousa, Nuno, Leite‐Almeida, Hugo, Sotiropoulos, Ioannis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783352/
https://ncbi.nlm.nih.gov/pubmed/26748966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12391
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