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Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging

Alternative splicing (AS) is a key regulatory mechanism for the development of different tissues; however, not much is known about changes to alternative splicing during aging. Splicing events may become more frequent and widespread genome‐wide as tissues age and the splicing machinery stringency de...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Rodríguez, Sofía A., Grochová, Diana, McKenna, Tomás, Borate, Bhavesh, Trivedi, Niraj S., Erdos, Michael R., Eriksson, Maria
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783335/
https://ncbi.nlm.nih.gov/pubmed/26685868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12433
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