Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues

BACKGROUND/OBJECTIVE: In mice, a high fat diet (HFD) induces obesity, insulin resistance and myostatin production. We tested whether inhibition of myostatin in mice can reverse these HFD-induced abnormalities. SUBJECTS/METHODS: C57BL/6 mice were fed a HFD for 16 weeks including the final 4 weeks som...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Dong, Jiangling, Dong, Yanjun, Dong, Yanlan, Chen, Fang, Mitch, William E., Zhang, Liping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783239/
https://ncbi.nlm.nih.gov/pubmed/26435323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2015.200
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