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High sensitivity of an Ha-RAS transgenic model of superficial bladder cancer to metformin is associated with ~ 240-fold higher drug concentration in urine than serum

While pharmacoepidemiologic and laboratory studies have supported the hypothesis that the anti-diabetic drug metformin may be useful in treating or preventing cancer, there is limited evidence to suggest which specific cancer sites may be particularly sensitive. Sensitivity likely is determined both...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cancer Ther
मुख्य लेखकों: Liu, Zhongbo, Yokoyama, Noriko N., Blair, Chris A., Li, Xuesen, Avizonis, Daina, Wu, Xue-Ru, Uchio, Edward, Youssef, Ramy, McClelland, Michael, Pollak, Michael, Zi, Xiaolin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783238/
https://ncbi.nlm.nih.gov/pubmed/26921394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0714-T
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