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TET1 methylation is associated with childhood asthma and traffic-related air pollution

BACKGROUND: Asthma is a complex disorder influenced by genetics and the environment. Recent findings have linked abnormal DNA methylation in T cells with asthma; however, the potential dysregulation of methylation in airway epithelial cells is unknown. Studies of mouse models of asthma have observed...

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Détails bibliographiques
Publié dans:J Allergy Clin Immunol
Auteurs principaux: Somineni, Hari K., Zhang, Xue, Myers, Jocelyn M. Biagini, Kovacic, Melinda Butsch, Ulm, Ashley, Jurcak, Noelle, Ryan, Patrick H., Hershey, Gurjit K. Khurana, Ji, Hong
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783231/
https://ncbi.nlm.nih.gov/pubmed/26684294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.10.021
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