A Common CCK-B Receptor Intronic Variant in Pancreatic Adenocarcinoma in a Hungarian Cohort

OBJECTIVES: Variant c.811+32C>A in intron 4 of the cholecystokinin-B receptor gene (CCKBR) was reported to correlate with higher pancreatic cancer risk and poorer survival. The variant was suggested to induce retention of intron 4, resulting in a new splice form with enhanced receptor activity. O...

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Publicado no:Pancreas
Main Authors: Balázs, Anita, Németh, Balázs Csaba, Ördög, Balázs, Hegyi, Eszter, Hritz, István, Czakó, László, Czimmer, József, Gódi, Szilárd, Csiszkó, Adrienn, Rakonczay, Zoltán, Párniczky, Andrea, Izbéki, Ferenc, Halász, Adrienn, Kahán, Zsuzsanna, Hegyi, Péter, Sahin-Tóth, Miklós
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783207/
https://ncbi.nlm.nih.gov/pubmed/26646278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000539
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