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Effects of serotonin and norepinephrine reuptake inhibitors on depressive- and impulsive-like behaviors and on monoamine transmission in experimental temporal lobe epilepsy

OBJECTIVE: Examine therapeutic potential of a selective serotonin reuptake inhibitor (SSRI) and a norepinephrine reuptake inhibitor (NERI) in an animal model of comorbidity between epilepsy, depression-like, and impulsive-like impairments. METHODS: Epilepsy was induced in male Wistar rats by LiCl an...

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Publicat a:Epilepsia
Autors principals: Kumar, Udaya, Medel-Matus, Jesus-Servando, Redwine, Hannah M., Shin, Don, Hensler, Julie G., Sankar, Raman, Mazarati, Andrey
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783206/
https://ncbi.nlm.nih.gov/pubmed/26813337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13321
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