Hif1α deletion reveals pro-neoplastic function of B cells in pancreatic neoplasia

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related deaths worldwide, with an exceedingly low 5-year survival rate. PDAC tumors are characterized by an extensive desmoplastic stromal response and hypovascularity, suggesting that tumor hypoxia could regulate PDAC initiation a...

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Detaylı Bibliyografya
Yayımlandı:Cancer Discov
Asıl Yazarlar: Lee, KyoungEun, Spata, Michelle, Bayne, Lauren J., Buza, Elizabeth L., Durham, Amy C., Allman, David, Vonderheide, Robert H., Simon, M. Celeste
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783189/
https://ncbi.nlm.nih.gov/pubmed/26715642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0822
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