Endothelial NADPH oxidase 4 protects ApoE−/− mice from atherosclerotic lesions

Vascular reactive oxygen species (ROS) are known to be involved in atherosclerosis development and progression. NADPH oxidase 4 (Nox4) is a constitutively active ROS-producing enzyme that is highly expressed in the vascular endothelium. Nox4 is unique in its biology and has been implicated in vascul...

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Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Craige, Siobhan M., Kant, Shashi, Reif, Michaella, Chen, Kai, Pei, Yongmei, Angoff, Rebecca, Sugamura, Koichi, Fitzgibbons, Timothy, Keaney, John F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783146/
https://ncbi.nlm.nih.gov/pubmed/26169727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.07.004
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