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A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance

In eutherians, the placenta acts as a barrier and conduit at the maternal-fetal interface. Syncytiotrophoblasts, the multinucleated cells that cover the placental villous tree surfaces of the human placenta, are directly bathed in maternal blood and are formed by the fusion of progenitor cytotrophob...

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Pubblicato in:Sci Adv
Autori principali: McConkey, Cameron A., Delorme-Axford, Elizabeth, Nickerson, Cheryl A., Kim, Kwang Sik, Sadovsky, Yoel, Boyle, Jon P., Coyne, Carolyn B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783126/
https://ncbi.nlm.nih.gov/pubmed/26973875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501462
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