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Decreased Laminin Expression by Human Lung Epithelial Cells and Fibroblasts Cultured in Acellular Lung Scaffolds from Aged Mice

The lung changes functionally and structurally with aging. However, age-related effects on the extracellular matrix (ECM) and corresponding effects on lung cell behavior are not well understood. We hypothesized that ECM from aged animals would induce aging-related phenotypic changes in healthy inocu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Godin, Lindsay M., Sandri, Brian J., Wagner, Darcy E., Meyer, Carolyn M., Price, Andrew P., Akinnola, Ifeolu, Weiss, Daniel J., Panoskaltsis-Mortari, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783067/
https://ncbi.nlm.nih.gov/pubmed/26954258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150966
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