Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression

Cholangiocarcinoma (CCA) has a poor prognosis due to widespread intrahepatic spread. Aspartate β-hydroxylase (ASPH) is a transmembrane protein and catalyzes the hydroxylation of aspartyl and asparaginyl residues in calcium binding epidermal growth factor (cbEGF)-like domains of various proteins, inc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Chiung-Kuei, Iwagami, Yoshifumi, Aihara, Arihiro, Chung, Waihong, de la Monte, Suzanne, Thomas, John-Michael, Olsen, Mark, Carlson, Rolf, Yu, Tunan, Dong, Xiaoqun, Wands, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783022/
https://ncbi.nlm.nih.gov/pubmed/26954680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150336
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