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The maternal interleukin-17a pathway in mice promotes autismlike phenotypes in offspring

Viral infection during pregnancy has been correlated with increased frequency of autism spectrum disorder (ASD) in offspring. This observation has been modeled in rodents subjected to maternal immune activation (MIA). The immune cell populations critical in the MIA model have not been identified. Us...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Choi, Gloria B., Yim, Yeong S., Wong, Helen, Kim, Sangdoo, Kim, Hyunju, Kim, Sangwon V., Hoeffer, Charles A., Littman, Dan R., Huh, Jun R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782964/
https://ncbi.nlm.nih.gov/pubmed/26822608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad0314
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