Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity

Multiple studies have indicated that in addition to direct oncolysis, virotherapy promotes an antitumor cytotoxic T cell response important for efficacy. To study this phenomenon further, we tested three syngeneic murine sarcoma models that displayed varied degrees of permissiveness to oncolytic her...

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發表在:Mol Ther Oncolytics
Main Authors: Leddon, Jennifer L, Chen, Chun-Yu, Currier, Mark A, Wang, Pin-Yi, Jung, Francesca A, Denton, Nicholas L, Cripe, Kevin M, Haworth, Kellie B, Arnold, Michael A, Gross, Amy C, Eubank, Timothy D, Goins, William F, Glorioso, Joseph C, Cohen, Justus B, Grandi, Paola, Hildeman, David A, Cripe, Timothy P
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782947/
https://ncbi.nlm.nih.gov/pubmed/27119100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2014.10
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