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Antimelanoma CTL recognizes peptides derived from an ORF transcribed from the antisense strand of the 3′ untranslated region of TRIT1

Noncoding regions of the genome play an important role in tumorigenesis of cancer. Using expression cloning, we have identified a cytotoxic T lymphocyte (CTL)–defined antigen that recognizes a protein sequence derived from an open reading frame transcribed from the reverse strand in the 3′ untransla...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Swoboda, Rolf K, Somasundaram, Rajasekharan, Caputo-Gross, Laura, Marincola, Francesco M, Robbins, Paul, Herlyn, Meenhard, Herlyn, Dorothee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782943/
https://ncbi.nlm.nih.gov/pubmed/27119099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2014.9
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