Changes in the Structure and Function of ICC Networks in ICC Hyperplasia and Gastrointestinal Stromal Tumors

BACKGROUND & AIMS: Gastrointestinal stromal tumors (GISTs) express the receptor tyrosine kinase c-kit. Approximately 90% of GISTs have gain-of-function mutations in the Kit gene, which leads to its constitutive activation and drives malignant behavior of GISTs. Interstitial cells of Cajal (ICC)...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: KWON, JOONG GOO, HWANG, SUNG JIN, HENNIG, GRANT W., BAYGUINOV, YULIA, MCCANN, CONOR, CHEN, HUI, ROSSI, FERDINAND, BESMER, PETER, SANDERS, KENTON M., WARD, SEAN M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782934/
https://ncbi.nlm.nih.gov/pubmed/19032955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.10.031
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