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Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications

BACKGROUND: Across species, diversity at the Major Histocompatibility Complex (MHC) is critical to disease resistance and population health; however, use of MHC diversity to quantify the genetic health of populations has been hampered by the extreme variation found in MHC genes. Next generation sequ...

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Pubblicato in:BMC Genomics
Autori principali: Grogan, Kathleen E., McGinnis, Gwendolyn J., Sauther, Michelle L., Cuozzo, Frank P., Drea, Christine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782575/
https://ncbi.nlm.nih.gov/pubmed/26957424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2503-y
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