Efficient derivation of dopaminergic neurons from SOX1(−) floor plate cells under defined culture conditions

BACKGROUND: Parkinson’s disease (PD) is a severe neurodegenerative disease associated with loss of dopaminergic neurons. Derivation of dopaminergic neurons from human embryonic stem cells (hESCs) could provide new therapeutic options for PD therapy. Dopaminergic neurons are derived from SOX(−) floor...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Li, Mingming, Zou, Yu, Lu, Qiqi, Tang, Ning, Heng, Alexis, Islam, Intekhab, Tong, Huei Jinn, Dawe, Gavin S., Cao, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782356/
https://ncbi.nlm.nih.gov/pubmed/26956435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0251-6
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