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A novel enrichment strategy reveals unprecedented number of novel transcription start sites at single base resolution in a model prokaryote and the gut microbiome

BACKGROUND: The initiating nucleotide found at the 5’ end of primary transcripts has a distinctive triphosphorylated end that distinguishes these transcripts from all other RNA species. Recognizing this distinction is key to deconvoluting the primary transcriptome from the plethora of processed tran...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Ettwiller, Laurence, Buswell, John, Yigit, Erbay, Schildkraut, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782308/
https://ncbi.nlm.nih.gov/pubmed/26951544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2539-z
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