Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin

Plakin proteins form critical connections between cell junctions and the cytoskeleton; their disruption within epithelial and cardiac muscle cells cause skin-blistering diseases and cardiomyopathies. Envoplakin has a single plakin repeat domain (PRD) which recognizes intermediate filaments through a...

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Pubblicato in:Nat Commun
Autori principali: Fogl, Claudia, Mohammed, Fiyaz, Al-Jassar, Caezar, Jeeves, Mark, Knowles, Timothy J., Rodriguez-Zamora, Penelope, White, Scott A., Odintsova, Elena, Overduin, Michael, Chidgey, Martyn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782060/
https://ncbi.nlm.nih.gov/pubmed/26935805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10827
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