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Mechanisms of metabolic dysfunction in cancer-associated cachexia

Metabolic dysfunction contributes to the clinical deterioration observed in advanced cancer patients and is characterized by weight loss, skeletal muscle wasting, and atrophy of the adipose tissue. This systemic syndrome, termed cancer-associated cachexia (CAC), is a major cause of morbidity and mor...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Petruzzelli, Michele, Wagner, Erwin F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782044/
https://ncbi.nlm.nih.gov/pubmed/26944676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276733.115
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