IL-6 Inhibition Reduces STAT3 Activation and Enhances the Antitumor Effect of Carboplatin

Recent studies suggest that tumor-associated macrophage-produced IL-6 is an important mediator within the tumor microenvironment that promotes tumor growth. The activation of IL-6/STAT3 axis has been associated with chemoresistance and poor prognosis of a variety of cancers including colorectal carc...

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Dettagli Bibliografici
Pubblicato in:Mediators Inflamm
Autori principali: Wang, Zhi-Yong, Zhang, Jun-Ai, Wu, Xian-Jin, Liang, Yan-Fang, Lu, Yuan-Bin, Gao, Yu-Chi, Dai, You-Chao, Yu, Shi-Yan, Jia, Yan, Fu, Xiao-Xia, Rao, Xiaoquan, Xu, Jun-Fa, Zhong, Jixin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781984/
https://ncbi.nlm.nih.gov/pubmed/27006530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8026494
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