Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes.

We have recently shown that the Alzheimer disease 40-residue amyloid beta-protein [A beta P-(1-40)] can form cation-selective channels when incorporated into planar lipid bilayers by fusion of liposomes containing the peptide. Since A beta P-(1-40) comprises portions of the putative extracellular an...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Arispe, N, Pollard, H B, Rojas, E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504270/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10573
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