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DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments

The DNA adenine methyltransferase identification (DamID) assay is a powerful method to detect protein-DNA interactions both locally and genome-wide. It is an alternative approach to chromatin immunoprecipitation (ChIP). An expressed fusion protein consisting of the protein of interest and the E. col...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Wu, Feinan, Olson, Brennan G., Yao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781701/
https://ncbi.nlm.nih.gov/pubmed/26862720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53620
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