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Isolation of Infiltrating Leukocytes from Mouse Skin Using Enzymatic Digest and Gradient Separation

Dissociating murine skin into a single cell suspension is essential for downstream cellular analysis such as the characterization of infiltrating immune cells in rodent models of skin inflammation. Here, we describe a protocol for the digestion of mouse skin in a nutrient-rich solution with collagen...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Benck, Charles J., Martinov, Tijana, Fife, Brian T., Chatterjea, Devavani
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781699/
https://ncbi.nlm.nih.gov/pubmed/26863129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53638
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