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Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological Conditions

Pharmacological treatment in animal models of cerebral disease imposes the problem of repeated injection protocols that may induce stress in animals and result in impermanent tissue levels of the drug. Additionally, drug delivery to the brain is delicate due to the blood brain barrier (BBB), thus si...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Sanchez-Mendoza, Eduardo H., Carballo, Jeismar, Longart, Marines, Hermann, Dirk M., Doeppner, Thorsten R.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781651/
https://ncbi.nlm.nih.gov/pubmed/26863287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52932
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