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A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-α) inhibitors, adalimumab and infliximab, for Crohn's disease.

BACKGROUND: Crohn's disease (CD) is a severe, lifelong disease characterised by inflammation of the gastrointestinal mucosa. The impact on patients and society is high as ill health can be lifelong and can negatively affect patients' quality of life. Costs to the NHS are high, particularly...

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Detalhes bibliográficos
Publicado no:Health Technol Assess
Main Authors: Dretzke, J, Edlin, R, Round, J, Connock, M, Hulme, C, Czeczot, J, Fry-Smith, A, McCabe, C, Meads, C
Formato: Artigo
Idioma:Inglês
Publicado em: NIHR Journals Library 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781107/
https://ncbi.nlm.nih.gov/pubmed/21291629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta15060
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