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Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
Alpha-synuclein (α-syn) protein is abundantly expressed mainly within neurons, and exists in a number of different forms - monomers, tetramers, oligomers and fibrils. During disease, α-syn undergoes conformational changes to form oligomers and high molecular weight aggregates that tend to make the p...
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| Publicado no: | J Vis Exp |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4781043/ https://ncbi.nlm.nih.gov/pubmed/26780369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53415 |
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