Adenovirus-Mediated siRNA Targeting CXCR2 Attenuates Titanium Particle-Induced Osteolysis by Suppressing Osteoclast Formation

BACKGROUND: Wear particle-induced peri-implant loosening is the most common complication affecting long-term outcomes in patients who undergo total joint arthroplasty. Wear particles and by-products from joint replacements may cause chronic local inflammation and foreign body reactions, which can in...

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Dettagli Bibliografici
Pubblicato in:Med Sci Monit
Autori principali: Wang, Chen, Liu, Yang, Wang, Yang, Li, Hao, Zhang, Ran-Xi, He, Mi-Si, Chen, Liang, Wu, Ning-Ning, Liao, Yong, Deng, Zhong-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2016
Soggetti:
Lab/In Vitro Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780823/
https://ncbi.nlm.nih.gov/pubmed/26939934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.897243
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