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New Insights into the Conversion of Versicolorin A in the Biosynthesis of Aflatoxin B(1)

A crucial and enigmatic step in the complex biosynthesis of aflatoxin B(1) is the oxidative rearrangement of versicolorin A to demethylsterigmatocystin. This step is thought to proceed by an oxidation–reduction–oxidation sequence, in which the NADPH-dependent oxidoreductase AflM catalyzes the enclos...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Conradt, David, Schätzle, Michael A., Haas, Julian, Townsend, Craig A., Müller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780671/
https://ncbi.nlm.nih.gov/pubmed/26266881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06770
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