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Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein

O-glycosylation of Ser and Thr residues is an important process in all organisms, which is only poorly understood. Such modification is required for the export and function of adhesin proteins that mediate the attachment of pathogenic Gram-positive bacteria to host cells. Here, we have analyzed the...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Chen, Yu, Seepersaud, Ravin, Bensing, Barbara A., Sullam, Paul M., Rapoport, Tom A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780648/
https://ncbi.nlm.nih.gov/pubmed/26884191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600494113
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