Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery.

Mammalian skin owes its remarkable barrier function to its outermost and dead layer, the stratum corneum. Transdermal transport through this region occurs predominantly through intercellular lipids, organized largely in bilayers. Electroporation is the creation of aqueous pores in lipid bilayers by...

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Bibliographic Details
Main Authors: Prausnitz, M R, Bose, V G, Langer, R, Weaver, J C
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47805/
https://ncbi.nlm.nih.gov/pubmed/8248137
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