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pH regulation of amphotericin B channels activity in the bilayer lipid membrane

BACKGROUND: Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of systemic fungal infections in spite of its secondary effects. The pH plays a crucial role in modulating biophysical features of ion channels in the bilayer lipid membranes. AIM: In this study, the role of...

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Detalhes bibliográficos
Publicado no:J Nat Sci Biol Med
Main Authors: Shahmoradi, Tahereh, Sepehry, Hamid, Ashrafpour, Manuchehr
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780175/
https://ncbi.nlm.nih.gov/pubmed/27003977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-9668.175082
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