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Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury
Succinylation refers to modification of lysine residues with succinyl groups donated by succinyl-CoA. Sirtuin5 (Sirt5) is a mitochondrial NAD(+)-dependent deacylase that catalyzes the removal of succinyl groups from proteins. Sirt5 and protein succinylation are conserved across species, suggesting f...
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| Udgivet i: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780049/ https://ncbi.nlm.nih.gov/pubmed/26388266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.09.005 |
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