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IL-10(+) innate-like B cells are part of the skin immune system and require α4β1 integrin to migrate between the peritoneum and inflamed skin()

The skin is an important barrier organ and frequent target of autoimmunity and allergy. Here we found innate-like B cells that expressed the anti-inflammatory cytokine IL-10 in the skin of humans and mice. Unexpectedly, innate-like B1 and conventional B2 cells showed differential homing capacities w...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Geherin, Skye A., Gómez, Daniela, Glabman, Raisa A., Ruthel, Gordon, Hamann, Alf, Debes, Gudrun F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779667/
https://ncbi.nlm.nih.gov/pubmed/26851219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403246
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