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The N-terminus of the yeast G protein-coupled receptor Ste2p plays critical roles in surface expression, signaling, and negative regulation

G protein-coupled receptors (GPCRs) are found in all eukaryotic cells examined to date where they function as membrane-bound proteins that bind a multitude of extracellular ligands to initiate intracellular signal transduction systems controlling cellular physiology. GPCRs have seven heptahelical me...

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Bibliografske podrobnosti
izdano v:Biochim Biophys Acta
Main Authors: Uddin, M. Seraj, Hauser, Melinda, Naider, Fred, Becker, Jeffrey M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779653/
https://ncbi.nlm.nih.gov/pubmed/26707753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2015.12.017
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