Characterization of neuropathology in the HIV-1 transgenic rat at different ages

The transgenic HIV-1 rat (Tg) is a commonly used neuroHIV model with documented neurologic/behavioral deficits. Using immunofluorescent staining of the Tg brain, we found astrocytic dysfunction/damage, as well as dopaminergic neuronal loss/dysfunction, both of which worsening significantly in the st...

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Publicado en:J Neuroimmunol
Autores principales: Reid, William C, Ibrahim, Wael G, Kim, Saejeong J., Denaro, Frank, Casas, Rafael, Lee, Dianne E, Maric, Dragan, Hammoud, Dima A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779503/
https://ncbi.nlm.nih.gov/pubmed/26943969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.01.022
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