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Elevation and persistence of CD8 T-cells in HIV infection: the Achilles heel in the ART era

INTRODUCTION: HIV infection leads to a disturbed T-cell homeostasis, featured by a depletion of CD4 T-cells and a persistent elevation of CD8 T-cells over disease progression. Most effort of managing HIV infection has been focused on CD4 T-cell recovery, while changes in the CD8 compartment were rel...

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Detalhes bibliográficos
Publicado no:J Int AIDS Soc
Main Authors: Cao, Wei, Mehraj, Vikram, Kaufmann, Daniel E, Li, Taisheng, Routy, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: International AIDS Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779330/
https://ncbi.nlm.nih.gov/pubmed/26945343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.19.1.20697
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