High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients with myelodysplastic syndrome

BACKGROUND: Despite the efficacy of decitabine treatment in myelodysplastic syndrome (MDS), no definite predictor of response is known. In this study, we investigated whether the expression levels of human equilibrative nucleoside transporter 1 (hENT1), hENT2, deoxycytidine kinase (DCK) and cytidine...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Wu, Lingyun, Shi, Wenhui, Li, Xiao, Chang, Chunkang, Xu, Feng, He, Qi, Wu, Dong, Su, Jiying, Zhou, Liyu, Song, Luxi, Xiao, Chao, Zhang, Zheng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779250/
https://ncbi.nlm.nih.gov/pubmed/26944860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0817-9
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