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The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity

Malignant transformations are often associated with aberrant glycosylation processes that lead to the expression of new carbohydrate antigens at the surface of tumor cells. Of these carbohydrate antigens, the Tn antigen is particularly highly expressed in many carcinomas, especially in breast carcin...

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Détails bibliographiques
Publié dans:Cancer Immunol Immunother
Auteurs principaux: Laubreton, Daphné, Bay, Sylvie, Sedlik, Christine, Artaud, Cécile, Ganneau, Christelle, Dériaud, Edith, Viel, Sophie, Puaux, Anne-Laure, Amigorena, Sebastian, Gérard, Catherine, Lo-Man, Richard, Leclerc, Claude
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779142/
https://ncbi.nlm.nih.gov/pubmed/26847142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1802-0
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