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Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies

A key aspect of TB pathogenesis that maintains Mycobacterium tuberculosis in the human population is the ability to cause necrosis in pulmonary lesions. As co-evolution shaped M. tuberculosis (M.tb) and human responses, the complete TB disease profile and lesion manifestation are not fully reproduce...

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Detalhes bibliográficos
Publicado no:Semin Immunopathol
Main Authors: Kramnik, Igor, Beamer, Gillian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779126/
https://ncbi.nlm.nih.gov/pubmed/26542392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-015-0538-9
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