Pre-existing Antibody: Biotherapeutic Modality-Based Review

Pre-existing antibodies to biotherapeutic drugs have been detected in drug-naïve subjects for a variety of biotherapeutic modalities. Pre-existing antibodies are immunoglobulins that are either specific or cross-reacting with a protein or glycan epitopes on a biotherapeutic compound. Although the ex...

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Veröffentlicht in:AAPS J
Hauptverfasser: Gorovits, Boris, Clements-Egan, Adrienne, Birchler, Mary, Liang, Meina, Myler, Heather, Peng, Kun, Purushothama, Shobha, Rajadhyaksha, Manoj, Salazar-Fontana, Laura, Sung, Crystal, Xue, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779092/
https://ncbi.nlm.nih.gov/pubmed/26821802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-016-9878-1
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