A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology

CD8 T cells are involved in pathogen clearance and infection-induced pathology in respiratory syncytial virus (RSV) infection. Studying bulk responses masks the contribution of individual CD8 T cell subsets to protective immunity and immunopathology. In particular, the roles of subdominant responses...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Liu, Jie, Haddad, Elias K., Marceau, Joshua, Morabito, Kaitlyn M., Rao, Srinivas S., Filali-Mouhim, Ali, Sekaly, Rafick-Pierre, Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778879/
https://ncbi.nlm.nih.gov/pubmed/26943673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005486
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