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High Throughput Sequencing Identifies Misregulated Genes in the Drosophila Polypyrimidine Tract-Binding Protein (hephaestus) Mutant Defective in Spermatogenesis

The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during spermatogenesis. The heph(2) mutation in this gene results in a specific defect in spermatogenesis, causing aberrant spermatid individualization and male sterility. However, the array of molecula...

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Publicat a:PLoS One
Autors principals: Sridharan, Vinod, Heimiller, Joseph, Robida, Mark D., Singh, Ravinder
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778870/
https://ncbi.nlm.nih.gov/pubmed/26942929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150768
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