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Identification of a Short Cell-Penetrating Peptide from Bovine Lactoferricin for Intracellular Delivery of DNA in Human A549 Cells

Cell-penetrating peptides (CPPs) have been shown to deliver cargos, including protein, DNA, RNA, and nanomaterials, in fully active forms into live cells. Most of the CPP sequences in use today are based on non-native proteins that may be immunogenic. Here we demonstrate that the L5a CPP (RRWQW) fro...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Liu, Betty R., Huang, Yue-Wern, Aronstam, Robert S., Lee, Han-Jung
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778846/
https://ncbi.nlm.nih.gov/pubmed/26942714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150439
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