The pro-apoptotic effects of TIPE2 on AA rat fibroblast-like synoviocytes via regulation of the DR5–caspase–NF-κB pathway in vitro

TIPE2, also known as TNFAIP8L2, a member of the tumor necrosis factor-alpha-induced protein-8 (TNFAIP8) family, is known as an inhibitor in inflammation and cancer, and its overexpression induces cell death. We examined the role of TIPE2 with respect to adjuvant arthritis (AA)-associated pathogenesi...

Full description

Saved in:
Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Shi, Chunyan, Zhang, Shifeng, Hong, Shifu, Pang, Jinglong, Yesibulati, Yeletai, Yin, Ping, Zhuang, Guohong
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778775/
https://ncbi.nlm.nih.gov/pubmed/27013892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S92907
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items